"The Strongest Woman in the Universe" is the eighteenth episode in the Outlaw Star series. The episode aired April 30 on TV Network in Japan and February 7, 2001 on Toonami in North America.
Fred Luo convinces Gene and the crew of the Outlaw Star to enter the Universal Strongman Tournament to defeat a woman, named Reiko Ando, he promised to marry if she won the tournament five times in a row.
- One of Reiko Ando's opponents sports a pair of boxing gloves, yet there seems to be no rule in the tournament stating the required use of any such equipment.
- The magazine Gene is holding near the end of the episode has the title 'SUNRISE 10' - a reference to the studio which produced the animation for Outlaw Star: Sunrise Studios.